RESUMO
AIM: The purpose of this study was to compare gender differences in the prevalence of oral lesions in HIV-infected Brazilian adults. METHODOLOGY: A retrospective study was conducted of medical records from HIV/AIDS patients from 1993 to 2004. Oral lesions were only included in this study if definitively diagnosed through microscopic analysis, therapeutic test or according to EC-Clearing house criteria. RESULTS: A total of 750 men and 237 women were included in the study. Statistically significant differences were observed only for oral hairy leukoplakia, Kaposi sarcoma and lymphadenopathy (P < 0.01). However, a model of logistic regression showed that only oral hairy leukoplakia presented a significant association with gender and males had a significantly likelihood (four times higher than females) of presenting with this oral manifestation [OR 4.3 (95% CI: 1.39-13.36)]. CONCLUSION: These data shows that oral manifestations are less prevalent in females than in males, particularly oral hairy leukoplakia.
Assuntos
Infecções por HIV/complicações , Doenças da Boca/etiologia , Adolescente , Adulto , Brasil/epidemiologia , Candidíase Bucal/epidemiologia , Candidíase Bucal/etiologia , Feminino , Gengivite Ulcerativa Necrosante/epidemiologia , Gengivite Ulcerativa Necrosante/etiologia , Infecções por HIV/epidemiologia , Humanos , Leucoplasia Pilosa/epidemiologia , Leucoplasia Pilosa/etiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Doenças da Boca/epidemiologia , Prevalência , Estudos Retrospectivos , Fatores Sexuais , Fatores Socioeconômicos , Adulto JovemRESUMO
Introdução - Vários estudos apontam para a importância do diagnóstico da leucoplasia pilosa oral (OHL) no diagnóstico e prognóstico da AIDS. Raros estudos utilizam a citopatologia como recurso da OHL, particularmente após a descrição de sua forma subclínica. O objetivo deste trabalho foi investigar a prevalência da leucoplasia pilosa oral em indivíduos soropositivos para o HIV. material e métodos - Realizou-se a oroscopia e raspagem bilateral das bordas laterais da língua, em 676 pacientes HIV+. O critério diagnóstico foi a a identificação das alterações nucleares (inclusão Cowdry A e núcleos em vidro fosco e em colar) representativas do efeito citopático do Vírus epstein-Barr (EBV). Resultados - Identificou-se OHL em 179 (27 por cento) dos 676 pacientes, sendo em 65 (10 por cento) OHL clínica e em 114 (17 por cento) OHL subclínica...
Introduction - Accurate diagnosis of oral hayry leukoplakia (OHL) is important because it many be an early indicator of undiagnosed HIV infection and AIDS's prognostic. Few studies tested cytopathology as a method for diagnosis of OHL, particularly after the description of it subclinical stage. Our purpose was to investigated the lateral borders of tongues of 676 patients. OHLwas considered as a diagnosis only when nuclear changes caused by Epstein-Barr Virus (Cowdry tupe A inclusion, ground glass and nuclear beading) were presents. Results - We identified OHL in 179 (27 percent) of the 676 patients, that 65 (10 percent) were clinica OHL and 114 (17 percent) were OHL in subclinical stage...
Assuntos
Infecções por HIV , Leucoplasia Pilosa , Síndrome de Imunodeficiência AdquiridaRESUMO
A genotype in the IL-1 gene cluster is associated with an increased risk of periodontitis. We investigated whether polymorphisms in the IL-1A +4845 and IL-1B +3954 loci affect the periodontal status of HIV-infected Brazilians on HAART. HIV-positive and HIV-negative subjects with periodontitis were genotyped for IL-1 by polymerase chain reaction and restriction enzyme digestion. Only 11.4% of patients were genotype positive. No associations between genotype positivity and HIV infection or periodontal status were found in this population.
